Table 6.
Genetic Correlations of SIS Scales and Schizophrenia
| Genetic Correlation with Schizophrenia | ||
|---|---|---|
| Scale | Rg | p-value |
| Observation | ||
| Guardedness† | 0.470 | .043 |
| Organization of Speech/Thought† | 0.259 | .210 |
| Social/Interpersonal Functioning† | 0.212 | .238 |
| Affect† | 0.217 | .260 |
| Irritability†* | 0.209 | .375 |
| Rapport† | 0.016 | .948 |
| Odd/Eccentric Behavior†* | −0.035 | .898 |
| Self-Report | ||
| Social Isolation | 0.247 | .140 |
| Sexual Anhedonia | 0.184 | .334 |
| Anger to Perceived Slights* | 0.178 | .510 |
| Suspiciousness* | 0.177 | .438 |
| Pathological Jealousy | 0.161 | .364 |
| Psychotic-like Phenomena | 0.035 | .907 |
| Introversion | 0.029 | .884 |
| Sensitivity | −0.034 | .848 |
| Restricted Emotion | −0.041 | .822 |
| Social Anxiety* | −0.111 | .614 |
| Ideas of Reference: Remarks* | −0.199 | .364 |
| Illusions* | −0.226 | .211 |
| Magical Thinking* | −0.304 | .099 |
| Ideas of Reference: Watched* | −0.350 | .099 |
Note: Sample is unaffected pedigree members and controls (n = 568). Covariates are age and sex.
*
Dichotomized scale: symptoms absent = 0, present = 1.
†
Interviewer observation – other scales are based on participant self-report.