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. Author manuscript; available in PMC: 2013 Jul 4.
Published in final edited form as: J Am Chem Soc. 2012 Jun 22;134(26):10815–10818. doi: 10.1021/ja305100g

Table 3.

Scope of the N(1), N(10) Indole Acetamide Componenta,b

graphic file with name nihms388787u2.jpg
entry R PG yield (%) ee (%)
1 Me Bn 96 > 99
2 Bn Bn 96 > 99
3c Allyl Bn 92 > 99
4 H Bn 80 90
5 H Me 98 93
6 H H 86 95
7 Me H 92 > 99
8 Me Me 96 97
a

Absolute configuration assigned by chemical correlation or analogy.

b

Enantiomeric excess determined by chiral HPLC analysis.

c

Reaction performed at rt.