Table 2.

Sample federated queries for Diabetes Mellitus (*Bio2RDF is not part of LODD)

Query description	LODD datasets to be queried
Q1. Find all patients having a side effect of Prandin after being administered.	RxNorm, SIDER
Q2. Find all FDA approved drugs for DM, and identify the patients that were being administered those drugs by drug class.	RxNorm, DailyMed
Q3. What genes or biomarkers are associated with DM as published in the literature and find their interaction pathway information?	Diseasome, Bio2RDF*
Q4. A variant of HNF4α is known to have a strong correlation with DM predisposition. Find all patients administered with drugs that target HNF4α.	RxNorm, DrugBank, Diseasome, ChemBL
Q5. Find all patients that are on Sulfonylureas, Metformin, Metglitinides, and Thiazolinediones, or combinations of them?	RxNorm, DrugBank, DailyMed
Q6. Find all patients taking Alpha-glucosidase inhibitors.	RxNorm, DrugBank