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. 2012 Jun 13;32(24):8158–8172. doi: 10.1523/JNEUROSCI.0251-12.2012

Figure 8.

Figure 8.

Cytoplasmic dynein is required for DCV trafficking in DB motor neuron dendrites in wild-type and cdk-5 mutant animals. A, Schematic diagram of a DB motor neuron (top panel). The boxed region denotes that the dendrite was imaged for data presented in A. Quantification of the direction of INS-22::Venus puncta movement in DB dendrites of wild-type (n = 34), cdk-5(gm336) (n = 36), dhc-1(js319) (n = 21), and cdk-5;dhc-1 (n = 29) double-mutant dendrites (bottom panel). B, Schematic diagram of a DB motor neuron (top panel). The boxed region denotes that the distal dendrite tip was imaged for data presented in B and C. Representative images of GFP::DLI-1 accumulations at the distal tip of DB7 dendrites in wild-type and cdk-5(gm336) mutant animals (bottom panels). C, Quantification of GFP::DLI-1 puncta intensity at the tip of DB7 dendrites in wild-type (n = 29) and cdk-5 (n = 23) mutant animals. Values that differ significantly (Tukey–Kramer test) from wild type (marked by symbols above each bar) or from other genotypes (comparisons marked by brackets) are denoted on the graphs (**p < 0.001; #p < 0.05; ns, p > 0.05).