. Author manuscript; available in PMC: 2012 Jul 9.

Published in final edited form as: Stress. 1998 Jul;2(3):159–169. doi: 10.3109/10253899809167280

TABLE III.

Effect of CRH antagonist infusion on ADX-induced granule cell death

Treatment:	Dentate Gyrus Region
Treatment:	Septal	Middle	Temporal
Sham-ADX	0.67 ± 0.2	0.38 ± 0.7	0.66 ± 0.33
ADX	10.7 ± 1.6^*	17.0 ± 3.9^*	15.0 ± 3.2^*
ADX-Antagonist	9.0 ± 1.4^*	22.4 ± 7.0^*	28.8 ± 18.1^*
ADX-Vehicle	16.3 ± 1.8^*	18.1 ± 2.1^*	22.4 ± 3.9^*

The number of apoptotic granule cells was determined in both the left and the right side of the dentate gyrus. The number of sections and the anatomic boundaries of the septal, middle, and temporal regions of the hippocampal formation have been defined in the Methods’ section.

Treatment group medians are significantly different from the control group’s (p < 0.05; Kruskal-Wallis non-parametric ANOVA test). ADX-Vehicle is not significantly different from ADX-Antagonist (post-hoc Dunn’s test).