Table 2. Effects of cyclosporine on cerebral cortical glutathione levels after hypoxic-reoxygenation (H-R).
GSH(nmol/mg protein) | GSSG(nmol/mg protein) | GSSG:GSHRatio | |
H-R Control | 229.3±20.4 | 27.2±1.5 | 0.12±0.01 |
CSA 2.5 mg/kg | 272.7±35.8 | 24.6±3.4 | 0.09±0.01* |
CSA 10 mg/kg | 303.5±54.1 | 16.8±2.1* | 0.06±0.01* |
Sham-operated | 330.1±47.3 | 18.2±3.5* | 0.06±0.01* |
p<0.05 vs. H–R controls (one-way ANOVA).