Table 5. Expression levels of classical genes targeted by TCDD.
ovary | Testis | |||||
control | TCDD | Fold-Change | control | TCDD | Fold-change | |
Ahrr | 18 | 79 | 4.2* | 14 | 48 | 3.34* |
Cyp1a1 | nd | nd | nd | nd | nd | nd |
Cyp1a2 | nd | nd | nd | nd | nd | nd |
Cyp1b1 | 1419 | 2300 | 1.63* | 1079 | 1315 | 1.22 |
Cyp2s1 | 66 | 55 | 0.83 | 65 | 54 | 0.83 |
Nqo1 | 350 | 470 | 1.34* | 303 | 444 | 1.46 |
Gsta1 | 13200 | 12800 | 0.96 | 7705 | 7652 | 0.99 |
Aldh3a1 | nd | nd | nd | nd | nd | nd |
Ugt1a6 | 210 | 273 | 1.3 | 381 | 436 | 1.14 |
Data were obtained using ovaries of 14 days of age and testes of 5 days of age.
p<0.05; nd, not detectable.