Table 5. Plasma concentrations of (an)orexigenic peptides, glucose and cortisol, estimation of insulin sensitivity and secretion using the HOMA model in AD subjects during withdrawal and controls.

	AD-T1 (n = 24)	AD-T2 (n = 24)	AD-T3 (n = 24)	Controls (n = 20)
Leptin (µg/L)	7,7±5,3	8,6±6.0	7.0±5,5§§	5,1±3.7§
Leptin/BMI	0.30±0,17	0.33±0.20	0.27±0.18§§	0.21±0.15§
Ghrelin (pg/ml)	102.0±34.4	99.3±35.5	104.6±39.8	130.5±48.9#§
PYY (pg/ml)	110.9±37.3	110.1±31.5	113.8±38.7	91.5±21.4#§ ¶
GLP-1(pm/ml)	2.48±1.57	2.24±1.56	2.23±1.56	3.2±1.2§ ¶
Insulin (µU/ml)	3.8±1.6	5.2±2.8##	4.5±2.5	3.3±1.4§
Glycemia (mg/dl)	86.8±10.7	79.1±10.2#	83.5±13.2	84.6±8.1
HOMA %S	187.4±70.8	151.9±67.3#	178.4±82.0	200.7±83.9
HOMA %B	73.4±21.3	113.6±57.5#	85.6±25.3#§	70.9±15.6§ ¶
Cortisol (ng/ml)	447.5±154.4	419.7±131.4	350.2±139.4#§	234.3±57.6###§§§ ¶¶

Values are means ± SD.

^#p<0.05,

^##p<0.01, p<0.001 (compared to AD-T1).

^§p<0.05,

^§§p<0.01,

^§§§p<0.001 (compared to AD-T2).

^¶p<0.05,

^¶¶p<0.01 (compared to AD-T3).