Table 2.
Genotypea | Amountb | Increasec | Pd | |
---|---|---|---|---|
CDKN2A | 2 | 0.002577 | 16.8988 | 0.0173 |
1 | 0.001334 | 8.7482 | >0.05 | |
0 | 0.000153 | 1 | ||
CDKN2B | 2 | 0.000697 | 3.976 | 0.0087 |
1 | 0.000518 | 2.9567 | >0.05 | |
0 | 0.000175 | 1 | ||
MTAP | 2 | 0.009758 | 1.2412 | >0.05 |
1 | 0.009028 | 1.1484 | >0.05 | |
0 | 0.007862 | 1 |
The genotype is the number of copies of the case associated (CA) haplotype with 2=homozygous for the CA haplotype, 1=heterozygous, and 0 = no copies of the CA haplotype.
The amount of transcript is relative to the amount of B2M transcript and normalized by comparison to expression in testes.
Increase in expression of each gene in individuals carrying the CA haplotype compared to those without.
p-values were calculated by Wilcoxon rank sum on the distribution of relative expression levels within each genotype group.