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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Pediatr Crit Care Med. 2012 Jul;13(4):e210–e218. doi: 10.1097/PCC.0b013e318238b5cd

Table 3.

Study measurements (day 1) in septic patients with and without neutropeniaa

Laboratorya Septic with Neutropenia
n = 13		 Septic without Neutropenia
n = 17		 pb
ADMA (µmol/L) 0.30 (0.27–0.36) 0.51 (0.39–0.63) <0.001
Arginine (µmol/L) 13 (6–20) 8 (7–34) 0.76
Citrulline (µmol/L) 6 (5–10) 10 (4–13) 0.88
Ornithine (µmol/L) 30 (20–61) 22 (11–64) 0.76
Arg:ADMA 41.9 (17.3–67.5) 19.7 (14.3–53.9) 0.53
Citr:Arg 0.54 (0.50–1.22) 0.51 (0.40–0.86) 0.34
Arg:Orn 0.33 (0.17–0.48) 0.48 (0.39–0.88) 0.20
AC:FC 0.44 (0.38–1.78) 1.35 (0.96–2.58) 0.40
IL-6 (pg/mL) 618 (257–5547) 13 (0–134) 0.001
IL-8 (pg/mL) 1115 (33–6419) 9 (7–61) 0.006

ADMA, asymmetric dimethylarginine; Arg:ADMA, arginine:asymmetric dimethylarginine ratio; Citr:Arg, citrulline:arginine ratio; Arg:Orn, arginine:ornithine ratio; AC:FC, acylcarnitine:free carnitine ratio; IL, interleukin; AC:FC, acylcarnitine:free carnitine ratio

a

Median values (interquartile range), unless indicated; neutropenia = absolute neutrophil count < 500 thous/µL)

b

Comparisons made using Fisher’s exact test