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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: J Immunol. 2012 Jun 20;189(2):988–1001. doi: 10.4049/jimmunol.1103031

Figure 4. Renal LN F4/80hi intrinsic functional analysis.

Figure 4

A. Analytical strategy of renal LN “macrophage” functional analysis (q-value <0.05, fold-change ≥1.2 for the up-regulated genes and ≤0.8 for the down-regulated genes). B. Overlap of the defined tubulointerstitial and glomerular “macrophage genes”. Transcriptional networks generated using the literature-based Genomatix Bibliosphere software from the 103 tubulointerstitial-restricted genes, the 224 glomerular-restricted genes and the 110 genes shared by both compartments and mouse F4/80hi intrinsic macrophages (q-value<0.05, fold-change ≥1.2 for the up-regulated genes and ≤0.8 for the down-regulated genes). Respectively, the pictures display the 42/103, 78/110 and 120/224 genes that were co-cited in PubMed abstracts in the same sentence linked to a function word (B2 filter).