Table III.
Transcription factor analysis from the defined “tubulointerstitial and glomerular macrophage genes”, as assessed by Genomatix Bibliosphere software.
| 25 genes from the 224 “glomerular-restricted macrophage genes” having a binding site for PPARG (V$PERO) in their promoter | HMOX1 | CCR2 | SOAT1 | ID2 | ALAS1 | ITGAM | ACSL5 | |
| HMMR | ENO2 | VAV1 | BATF | PLIN2 | CD40 | AURKB | ||
| MMP2 | MAP4K4 | CD8A | OLR1 | SMAD7 | CFLAR | PLA2G7 | ||
| PCK2 | TGM2 | SMARCD3 | LMO4 | |||||
|
| ||||||||
| From the 110 “shared tubulointerstitial and glomerular macrophage genes”: | 14 genes having a binding site for IRF7 (V$IRFF) in their promoter | MGP | MYC | DOCK2 | IFI35 | LGALS3BP | ISG20 | OASL |
| MYD88 | IGFBP6 | IFIT1 | IFIH1 | RSAD2 | IFI44 | |||
| NRP1 | ||||||||
|
| ||||||||
| 27 genes having a binding site for MYC (V$EBOX) in their promoter | NCK1 | S100A4 | FAS | SERPING1 | CD44 | LGALS1 | ANXA1 | |
| DKK3 | VCAM1 | LTF | TIMP1 | CXCR4 | PLAC8 | CD38 | ||
| LYN | ZBTB16 | COL1A2 | RRM2 | NME1 | CCNB1 | HCK | ||
| MYD88 | SATB1 | IRF7 | RBP1 | LGALS3BP | HTATIP2 | |||
|
| ||||||||
| 24 genes from the 103 “tubulointerstitial- restricted macrophage genes” having a binding site for NFKB1 (V$NFKB) in their promoter | S100A6 | NPPA | C1R | ANXA2 | APOBEC2 | XBP1 | DPP4 | |
| THBS1 | SERPINE2 | TRAF3IP2 | TXNDC5 | GPR126 | PDGFB | TNC | ||
| MAP4K2 | VIM | TSPO | ADAM9 | ANXA5 | DYNLL1 | CLU | ||
| L1CAM | CD9 | ANXA3 | ||||||