Depletion of macrophage, B cells, and DCs and confirmation of depletion are described in Materials and Methods. A, Graft survival in mice depleted of macrophages by liposome clodronate (Lipo-Clodronate) at the time of donor ECDI-SPs infusions. B, Graft survival in mice depleted of B cells by anti-mCD20 at the time of donor ECDI-SPs infusions. C, Graft survival in CD11c-DTR mice depleted of CD11c+ DCs by treatment with DT at the time of donor ECDI-SPs infusions. P values for significant differences are shown.