Figure 4.
Platelets Present Antigen to T cells. A) In Vitro. WT or OT-I T cells were incubated with control buffer or platelets from WT or OVA-Tg mice. IL-2 was measured by ELISA (n=4 ± S.D., *P<0.01 vs WT). B) INFγ (n=4 ± S.D., *P<0.01 vs WT). C) In Vivo. WT or OT-I mice were given WT or OVA-Tg platelets i.v. and 48 hrs later plasma was isolated to measure IL-2 by ELISA. (n=4, ±S.D., *P<0.01 vs WT).