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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: J Immunol. 2012 Jun 15;189(2):916–923. doi: 10.4049/jimmunol.1200580

Figure 6.

Figure 6

Platelets present Plasmodium derived antigen to T cells. A) Platelets acquire and present antigen. OT-I T cells were incubated alone, with iRBC, or with iRBC and WT or β2M−/− platelets. 48hrs later T cell CD25 expression was determined by FACS. WT platelets increased OT-I T cell CD25 expression (n=4 ± S.D., *P<0.02 vs iRBC) and B) increased IL-2 production (n=4 ± S.D., *P<0.03 vs iRBC). C) Platelets were isolated from control mice or mice infected with PbA-OVA and MHCI-OVA measured by FACS (n=5 ± S.D., *P<0.05 vs Control).