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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Free Radic Biol Med. 2012 May 5;53(2):194–207. doi: 10.1016/j.freeradbiomed.2012.04.005

Fig. 7.

Fig. 7

Effect of metallothionein (MT) on low temperature (LT, 4°C, 3 months)-induced change in ER stress markers and ER stress-related apoptosis. A: Bip expression; B: Calregulin expression; C: IRE1α phosphorylation (normalized to total IRE1α); D: eIF2α phosphorylation (normalized to total eIF2α); E: CHOP expression; and F: Cleaved caspase-12 expression. Insets: Representative gels depicting ER stress markers using specific antibodies. GAPDH was used as the loading control. Mean ± SEM, n = 3 – 5 mice per group, * p < 0.05, NT: normal temperature.