Figure 1. InsR PCR primer design and standard plasmid template construction.
InsR-A and B isoform templates were synthesized and cloned into pUCminusMCS plasmid vectors. (A) InsR-A qPCR primers amplify a 50 bp region within the 404 bp encoded by exons 10 and 12. (B) InsR-B qPCR primers amplify a 42 bp region of the 440 bp encoded by exons 10, 11, and 12. A 20 bp ladder is shown.