Table 2.

Patient characteristics of cases evaluated for pAKT and SNO-Akt levels

Group	AGE	SEX	Post-mortem Interval	Neuropathology	GDS	Neuropsychology
Normal/(HIV-)	63	Female	8	Normal	N/A	Unknown
Normal//(HIV-)	69	Male	24	Normal	N/A	Unknown
Normal/(HIV-)	71	Male	2	Normal	N/A	Unknown
HIV+	51	Male	17	Normal	<0.5	Normal
HIV+	59	Female	15	HIV encephalitis	<0.5	Normal
HIV+	40	Male	13	Microglial nodule encephalitis	<0.5	Normal
HIV+	50	Male	15	Normal	0.67	MCMD
HIV+	55	Male	15	HIV encephalitis	2.37	HAD
HIV+	51	Male	48	HIV encephalitis, Leukoencephalopathy	2.94	HAD

HIV+: HIV-1 infected

HAD: HIV-associated dementia

MCMD: Minor cognitive and motor disorder

(HAD represents severe and MCMD represents mild forms of HAND)

GDS: Global Deficit score; >0.5 is a criterion for HAND

Brain region used: Frontal cortex