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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: J Immunol. 2012 Jun 20;189(2):1081–1093. doi: 10.4049/jimmunol.1200318

Figure 12. Lack of IL-21R on host B cells does not alter the priming and TFH differentiation of donor CD4+ T cells in Bm12→B6 cGVHD.

Figure 12

Bm12→B6 cGVHD was induced using CFSE labeled donor cells. A. Mean percentage of CD44hi and CD69hi donor cells detected as CFSE+ CD4+ T cells at 3 days after disease induction. B. Proliferation of donor CD4+ T cells detected by generational analysis of CFSE+ cells. C. Percentage of proliferating donor cells. D. Percentage of PD-1+CXCR5+ dTFH cells at 7 days after disease induction. Data are representative of two independent experiments; n=5 mice/group. **=p<0.01