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MRI-scan (T2-weighted images) of the brain during sunitinib therapy at (A) presentation with RPLS, (B) during everolimus therapy (six weeks after sunitinib was stopped) and (C) 2 weeks after cessation of everolimus. Extensive edema is evident in the right parieto-temporal, right parietal and left parieto-occipital areas of the brain. RPLS, reversible posterior leukoencephalopathy syndrome.
