Table I.

Review of 20 cases of oxaliplatin-induced acute-onset thrombocytopenia and hemorrhage.

Case	Gender	Age	Course	Platelet count	Platelet (after)	Onset	Symptoms	Treatment	Result
1	M	56	N/K	99000	6000	5 h	Purpura, gingivorrhagia	Steroids, transfusion	Recovery
2	M	52	9	182000	17000	1 day	Bleeding	Transfusion	Recovery
3	F	40	13	153000	80000	1 day	Back pain	No	Recovery
4	F	70	19	432000	2000	4 h	Skin rash	Transfusion	Recovery
5	M	60	14	143000	2000	1 h	Hematemesis	Transfusion	Recovery
6	F	79	15	221000	5000	4 h	Bleeding, purpura	Steroids, transfusion	Recovery
7	F	38	17	150000	13000	2 days	Abdominal pain, petechial hemorrhages	Transfusion	Recovery
8	F	55	10	136000	6000	24 h	Not mentioned	Transfusion	Recovery
9	F	59	20	253000	5000	8 h	Purpura, gingivorrhagia	Steroids, transfusion	Recovery
10	M	64	24	163000	4000	1 h	Back pain	Transfusion	Death
11	F	57	11	89000	17000	17 h	Bleeding	Transfusion	Recovery
12	F	50	15	119000	5000	7 h	Purpura, gingivorrhagia	Steroids, transfusion	Recovery
13	M	48	21	94000	1000	7 h	Purpura	Steroids, transfusion	Recovery
14	F	59	12	151000	20000	1 day	Petechial hemorrhages	Steroids, transfusion	Recovery
15	M	60	3	226000	4000	1 day	Petechial hemorrhages, tongue hematoma	IVIG infusion	Recovery
16	F	66	3	87000	66000	5–10 min	Skin rash	Steroids	Recovery
17	F	55	13	136000	8000	Immediately	Petechial hemorrhages	Steroids	Recovery
18	M	78	17	104000	15000	1.5 h	Coma	Steroids, transfusion, G-CSF	Death
19	F	66	25	N/K	22000	4 days	Fever up, general fatigue	Transfusion, HD	Recovery
Our case	F	55	9	135000	35000	2 days	Bleeding	Steroids, transfusion	Recovery

NK, not known; G-CSF, granulocyte colony-stimulating factor; HD, hemodialysis; IVIG, intravenous immunoglobulin.