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. 2012 Mar 7;23(6):647–657. doi: 10.1089/hum.2011.177

Table 1.

Calculated Coupling Control Ratios on ROUTINE (R), LEAK (L), and Noncoupled Respiration (E)

 
Respiration
Coupling CTL ratios
Cells ROUTINE LEAK ETS R/E L/E (R – L)/E
LHON CTL, 3 wk 9.91 4.16 13.93 0.711 0.298 0.413
LHON TFAM+mtDNA, 3 wk 12.62 5.04 16.13 0.782 0.312 0.470

The quantitative effects of three independent treatments with mtDNA+TFAM of LHON samples (n=11) over 3 weeks are shown with respect to untreated CTL cells.