Table 2.
Effects of Single Treatments with rhTFAM or rhTFAM+mtDNA
| |
Respiration |
Coupling CTL Ratios |
||||
|---|---|---|---|---|---|---|
| Cells | ROUTINE | LEAK | ETS | R/E | L/E | (R – L)/E |
| LS CTL, 2 wk | 11.01 | 1.97 | 24.20 | 0.45 | 0.08 | 0.37 |
| LS TFAM, 2 wk | 11.35 | 1.46 | 22.86 | 0.50 | 0.06 | 0.43 |
| LS TFAM+mtDNA, 2 wk | 15.70 | 3.60 | 20.51 | 0.77 | 0.18 | 0.59 |
The effects of single treatments with rhTFAM or rhTFAM+mtDNA on ROUTINE respiration (R), respiration with oligomycin (LEAK, L), and respiration with oligomycin and uncoupled with FCCP (ETS, E) were determined. The coupling CTL ratios were calculated as indicated.