Cytotoxicity effect of bortezomib (BTZ) and CR4056 in (A) A549, (B) H460, (C) RPMI 8226, and (D) H929 cell lines.
Notes: Results are expressed as mean of three independent experiments (percentage of cell survival, mean plus or minus standard deviation, with respect to the control); control value was set as 100%; **Significantly different from control (P < 0.01); ***Significantly different from control (P < 0.001); #Significantly different from BTZ (P < 0.01).
Abbreviation: DMSO, dimethyl sulfoxide.