Figure 3.
Defective chromatin organisation in post-stage 5 gemin3 mutant egg chambers. Hoescht-stained stage 8 egg chambers (posterior is top right) showing that the nurse cell chromosomes of gemin3R egg chambers retain a compact 'blob-like' morphology, instead of dissociating and decondensing to be uniformly distributed throughout the nucleus as is typical in wild type. Insert shows Hoescht-stained oocyte nucleus, which is frequently decondensed in the mutant in contrast to the wild type where it is typically condensed into a small round karyosome.