Table 2.
The association between baseline BMLs, dietary factors, and lipidsa
| Univariate | Multivariableb | |||
|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | |
| Dietary factors | ||||
| Energy intake | 1.12 (0.91, 1.36) | 0.285 | 1.07 (0.84, 1.35) | 0.592 |
| Total fat | 1.09 (0.89, 1.33) | 0.385 | 1.06 (0.84, 1.34) | 0.630 |
| Carbohydrate | 1.14 (0.93, 1.39) | 0.206 | 1.08 (0.85, 1.36) | 0.525 |
| Protein | 1.07 (0.88, 1.30) | 0.517 | 1.03 (0.82, 1.29) | 0.785 |
| Sugars | 1.13 (0.93, 1.39) | 0.217 | 1.11 (0.89, 1.39) | 0.344 |
| Individual fats | ||||
| Monounsaturated fat | 1.07 (0.88, 1.31) | 0.502 | 1.02 (0.81, 1.29) | 0.849 |
| Polyunsaturated fat | 0.96 (0.78, 1.17) | 0.672 | 0.92 (0.73, 1.15) | 0.455 |
| Saturated fat | 1.14 (0.94, 1.40) | 0.187 | 1.14 (0.90, 1.44) | 0.283 |
| Lipids | ||||
| Total cholesterol | 0.76 (0.61, 0.95) | 0.015 | 0.81 (0.63, 1.02) | 0.074c |
| Triglycerides | 1.00 (0.82, 1.22) | 0.996 | 0.90 (0.72, 1.13) | 0.384c |
| LDL cholesterol | 0.84 (0.68, 1.03) | 0.101 | 0.88 (0.69, 1.11) | 0.280c |
| HDL cholesterol | 0.77 (0.62, 0.95) | 0.016 | 0.89 (0.70, 1.14) | 0.357c |
aBML absent (226) versus present (168). Odds ratios (ORs) have been standardized. bAdjusted for age, sex, body mass index, smoking, cardiovascular diseases, diabetes, and radiographic osteoarthritis. cFurther adjusted for statin use. Boldface denotes a statistically significant result. BMLs, bone marrow lesions; 95% CI, 95% confidence interval; HDL, high-density lipoprotein; LDL, low-density lipoprotein; P, P value.