. 2012 Jun 15;5:121–138. doi: 10.2147/JPR.S30540

Table A6.

Mean (SD) SF-36 scores at baseline and at Weeks 6 and 12 using observed-case analysis (with and without the Week 9–12 data for the Substudy A population) and using the LOCF (without the Week 9–12 data for the Substudy A population) – main analysis population

Subscale or summary	Baseline (n = 195)	Observed-case analysis			LOCF

		Week 6 (n = 159)	Week 12		Week 6 (n = 185)	Week 12

			Without Substudy A (n = 125)	With Substudy A (n = 144)		Without Substudy A (n = 164)
Role-physical	33.5 (41.70)	54.2 (43.59)^a	65.0 (41.88)^a	61.8 (42.63)^a	53.1 (43.70)^a	57.9 (43.85)^a
Physical functioning^b	30.4 (19.36)	47.6 (23.52)^a	53.3 (25.56)^a	52.7 (25.47)^a	45.4 (24.78)^a	48.5 (26.99)^a
Bodily pain	32.5 (16.87)	54.0 (20.44)^a	62.4 (21.97)^a	61.0 (21.23)^a	51.7 (21.59)^a	56.4 (24.43)^a
General health^a	46.3 (16.55)	55.8 (18.77)^a	60.3 (20.04)^a	58.6 (19.78)^a	53.9 (19.01)^a	55.9 (20.97)^a
Vitality	46.8 (17.39)	56.1 (19.70)^a	60.0 (21.85)^a	58.5 (21.92)^a	55.1 (19.27)^a	56.9 (21.32)^a
Social functioning	66.1 (25.63)	76.5 (23.88)^a	82.7 (21.58)^a	81.9 (21.97)^a	75.5 (25.08)^a	78.3 (26.08)^a
Role-emotional	69.2 (41.44)	82.2 (35.73)^a	81.1 (36.01)^a	81.9 (35.01)^a	80.7 (36.54)^a	78.5 (37.61)^a
Mental health	63.1 (19.95)	72.1 (17.70)^a	75.0 (20.20)^a	73.8 (20.35)^a	70.5 (18.14)^a	72.0 (20.51)^a
Physical component	28.1 (8.51)	35.7 (10.20)^a	39.3 (10.58)^a	38.5 (10.56)^a	34.9 (10.35)^a	36.9 (11.24)^a
Mental component	50.7 (11.46)	53.7 (10.13)^a	54.1 (10.45)^a	53.9 (10.56)^a	53.2 (10.31)^a	53.1 (11.02)^a

Notes:

P < 0.05 for the change from baseline;

baseline, n = 194; Observed-case analysis: Week 6, n = 159; Week 12, without Substudy A, n = 125; Week 12, with Substudy A, n = 144; LOCF: Week 6, n = 184; Week 12, n = 163.

Abbreviations: SD, standard deviation; SF-36, Short Form-36; LOCF, last observation carried forward.