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The top panel shows the effects of pretreatment with four doses of i.m. methylphenidate or saline on responding for 5 μg/kg/injection i.v. methamphetamine or food. Each curve is the mean of three monkeys. The bottom panel shows the effects of pretreatment with saline or 0.56 mg/kg i.m. methylphenidate on responding for various self-administration doses of i.v. methamphetamine or saline (S). Each curve is the mean of results with four monkeys.
