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. Author manuscript; available in PMC: 2012 Jul 10.
Published in final edited form as: Semin Nucl Med. 2011 Jan;41(1):29–44. doi: 10.1053/j.semnuclmed.2010.08.005

Table 2.

11C-choline 40,42,44-66 and 18F-choline 67-81 PET clinical trials in prostate cancer

Tracer(s) Patient
number		 Disease stage Study
objective		 Sensitivity Specificity Year Group
11C-choline 10 Mixed Staging NA NA 1998 Hara T, et al.
11C-choline 23 Advanced Staging NA NA 2000 Kotzerke J, et al.
11C-choline 25 Early Staging NA NA 2002 De Jong IJ, et al.
11C-choline 67 Mixed Staging 80% 96% 2003 De Jong IJ, et al.
11C-choline 36 Mixed Restaging 38% NA 2003 De Jong IJ, et al.
11C-choline 14 Early Staging NA NA 2004 Sutinen E, et al.
11C-choline 36 Early Staging 66% 81% 2005 Farsad M, et al.
11C-choline 20 Early Staging 100% NA 2005 Yamaguchi T, et al.
11C-choline 13 Mixed Staging 56.3% 12.5% 2005 Yoshida S, et al.
11C-choline 43 Early Staging 66% 84% 2006 Martorana G, et al.
11C-choline 26 Early Staging NA NA 2006 Reske SN, et al.
11C-choline 50 Advanced Restaging 91% 50% 2007 Rinnab J, et al.
11C-choline 55 Early Staging 36% NA 2007 Rinnab J, et al
11C-choline 58 Early Staging 86.5% 62% 2007 Scher B, et al.
11C-choline 26 Early Staging 55% 86% 2007 Testa C, et al.
11C-choline 15 Recurrence Restaging NA NA 2008 Rinnab J, et al.
11C-choline 57 Mixed Staging 60% 97.6% 2008 Schiavina R, et al.
11C-choline 49 Early Staging 90.5% 85.7% 2008 Li X, et al.
11C-choline 41 Advanced Restaging 75-89% 40% 2009 Rinnab J, et al.
11C-choline 190 Advanced Restaging 73% 69% 2009 Castellucci P, et al
11C-choline 6 Advanced Restaging NA NA 2010 Winter A, et al
11C-choline 25 Recurrence Restaging 86% 100% 2010 Fucchio C, et al.
11C-choline, 18F-FDG 26 Early Staging 73% (31%) NA 2010 Watanabe H, et al.
11C-choline, 18F-FDG 100 Advanced Restaging 47% (27%) NA 2003 Picchio M, et
11C-choline, 11C-acetate, 12 Advanced Staging NA NA 2003 Kotzerke J, et al.
18F-FCH 17 Mixed Staging 93% 48% 2005 Kwee SA, et al.
18F-FCH 19 Early Restaging 100% NA 2005 Schmid DT, et al.
18F-FCH 26 Mixed Staging 60% 90% 2006 Kwee SA, et al.
18F-FCH 100 Advanced Restaging 98% 100% 2006 Cimitan M, et al.
18F-FCH 20 Advanced Staging 10% 80% 2006 Hacker A, et al.
18F-FCH 34 Advanced Restaging NA NA 2006 Heinisch M, et al.
18F-FCH 111 Mixed Staging 86% NA 2008 Husarik DB, et al.
18F-FCH 20 Early Staging NA NA 2008 Igerc I, et al
18F-FCH 15 Early Staging NA NA 2008 Kwee SA, et al.
18F-FCH 70 Advanced Staging 79% 97% 2009 Beheshti M, et al.
18F-FCH 20 Early Staging NA NA 2010 Steuber T, et al
18F-FCH 111 Mixed Staging 45-66% 96% 2010 Beheshti M, et al.
18F-FCH 25 Early Staging 100% 95% 2010 Poulsen MH, et al
18F-FCH, 1C-acetate, 11 (11) Advanced Restaging NA NA 2007 Vees H, et al.
18F-FCH, 18F-Fluoride 38 Mixed Staging 74% (81%) 99% (93%) 2008 Beheshti M, et al.