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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2011 Apr 20;38(11):1967–1976. doi: 10.1007/s00259-011-1810-4

Table 2.

Biodistribution results for 68Ga- DOTA-ZHER2:2891 and His6-ZTaq-Cys-DOTA-68Ga Affibody injection in nude mice bearing BT474, mean ± SD (n = 4).

68Ga- DOTA-ZHER2:2891 His6-ZTaq-Cys-DOTA-
68Ga

1 h after injection 3 h after injection 1 h after injection
Blood 1.13±0.39 0.28±0.0235 1.2±0.36

Heart 0.87±0.32 0.3±0.04

Lungs 1.9±0.49 0.56±0.07

Kidney 223±26 227±14.2 172.2±12.5

Spleen 0.9±0.22 0.49±0.03

Liver 2.04±0.25 1.7±0.49 1.3±0.2

Pancreas 0.6±0.05 0.38±0.031

Tumor 31±2.1 25.7±2.2 1.1±0.4

Bone 1.2±0.5 0.47±0.09

Small intestine 0.6±0.2 0.43±0.09

Muscle 0.4±0.09 0.14±0.02 0.2±0.1

Ratios:
T/Blood 27± 4.4 91.8± 13.5
T/Muscle 91.8± 13.7 128± 41