TABLE 4.

Secondary end points: Adverse effects

	D1PO				D2PO				D3PO				D4PO
Group	n	N	%	P	n	N	%	P	n	N	%	P	n	N	%	P
Nausea
Usual care + LAO	40	86	46.5	0.6474	32	80	40.0	0.2548	27	79	34.2	0.0769	21	69	30.4	0.5679
Usual care	43	85	50.6		26	84	31.0		17	81	21.0		17	69	24.6
Drowsy
Usual care + LAO	56	86	65.1	0.3218	41	79	51.9	0.5323	25	78	32.1	1.0000	22	69	31.9	0.5738
Usual care	62	85	72.9		39	84	46.4		26	80	32.5		18	68	26.5
Vomiting
Usual care + LAO	17	86	19.8	1.0000	6	80	7.5	0.7820	12	79	15.2	0.0148	11	69	15.9	0.1825
Usual care	16	85	18.8		8	84	9.5		3	81	3.7		5	69	7.2
Puritis
Usual care + LAO	28	86	32.6	0.2694	23	80	28.8	0.6133	27	79	34.2	0.1140	15	69	21.7	0.5143
Usual care	35	85	41.2		28	84	33.3		18	81	22.2		11	69	15.9
Dizziness
Usual care + LAO	29	86	33.7	0.8708	16	80	20.0	0.1518	13	79	16.5	1.0000	12	69	17.4	1.0000
Usual care	27	86	31.4		26	84	31.0		14	81	17.3		11	69	15.9
Other
Usual care + LAO
Usual care									1	64	1.6

D1PO, D2PO, D3PO, D4PO Postoperative days 1, 2, 3, 4; LAO Long-acting opioid