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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Thromb Haemost. 2011 Oct;9(10):2009–2019. doi: 10.1111/j.1538-7836.2011.04491.x

Fig. 6. cFIX antigen levels and anti-cFIX antibodies in BALB/c mice after intramuscular injection with AAV2/1, 2, or 2/8-CMV-cFIX-WPRE vectors at the dose of 1×1011 GC.

Fig. 6

A. Time course of cFIX expression levels in the plasma of mice following i.m. injection with different pseudotyped AAV vectors (mean ± SD, n=5). cFIX in AAV2/8-injected mice were statistically higher than that in AAV2/1 or AAV2-injected mice. * p<0.001, ANOVA, Dunnett test. B. Anti-cFIX-specific IgG1. Each line represents an individual mouse.