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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: J Thromb Haemost. 2011 Oct;9(10):2009–2019. doi: 10.1111/j.1538-7836.2011.04491.x

Figure 8. T cell response to the capsid by different AAV serotypes.

Figure 8

BALB/c mice were intramuscularly injected with AAV vectors at 1×1012 GC/mouse (n=3 per vector). Seven days after injection, splenocytes were isolated, pooled, and stimulated with H-2d-restricted dominant epitopes (AAV2: VPQYGYLTL; other serotypes: IPQYGYLTL) or medium alone for IFN-γ ELISPOT assay. Peptide-specific cells are presented as spot forming cells (SFC) per 106 splenocytes.