TABLE 2.
Twenty top-ranking genes with hypermethylated or hypomethylated promoters
| Hypermethylationa | Hypomethylationb | ||
|---|---|---|---|
| ADHFE1 | FLJ30834 | SFT2D3 | FLJ36046 |
| GPR75 | SLC18A3 | MAEL | LAMB1 |
| BOLL | WDR78 | EDG6 | SLC6A6 |
| SLC6A15 | KCNQ5 | LILRA4 | GPSM1 |
| ADAMTS5 | PRKAR1B | HIST1H2BO | MGC11257 |
| VGCNL1 | GABBR2 | GPR109A | INT1 |
| TFPI2 | PCDHGC4 | CARD14 | SLC6A18 |
| CUTL2 | ADCY1 | FLJ36116 | FLJ27365 |
| UNC5C | FIGN | GRAP | NUP50 |
| SPG20 | GALR2 | NRXN1 | ABHD7 |
a
twenty top-ranking genes hypermethylated in colorectal cancer tissue compared to normal colorectal mucosa, which were selected based on statistical significance
b
twenty top-ranking genes hypomethylated in colorectal cancer tissue compared to normal colorectal mucosa, which were selected based on statistical significance