Fig. 1.

Inhalation of beclin1 resulted in a synergistic anti-tumor effect with radiation in the lungs of K-ras^LA1 mice.

(a) The left lobe of the lungs were collected and fixed with 10% neutral formalin for the gross description of the tumors. Tumor nodules were counted, and sizes were measured with automated calipers. Dotted circles represent tumor nodules >1.0 mm. Arrows represent tumor nodules <1.0 mm. (b) Lungs were paraffin-sectioned at 3 µm and slides were stained with H&E for histopathological analysis. Magnification: ×400. Scale bar: 20 µm. Representative figures of five mice per group.