Table 1.
90% PRNT medians and geometric mean titers for different orthopoxvirus neutralization targets by vaccination regimen
| Orthopoxvirus neutralization target | Each vaccination regimen (n) |
All vaccines (n = 46) | ||
|---|---|---|---|---|
| MVA SC (20) | MVA IM (15) | Dryvax (11) | ||
| Dryvax | ||||
| 90% PRNT median (interquartile range) | 35.0 (13.0–95.5) | 14.0 (11.0–33.0) | 71.0 (29.0–167.0) | 32.5 (12.0–93.0) |
| GMT | 30.9 | 18.0 | 47.5 | 28.7 |
| MVA | ||||
| 90% PRNT median (interquartile range) | 245.0 (61.5–673.0) | 117.0 (92.0–247.0) | 10.0 (4.0–59.0) | 110.5 (18.0–345.0) |
| GMT | 152.9 | 156.0 | 15.5 | 89.3 |
| Variola | ||||
| 90% PRNT median (interquartile range) | 63.4 (49.9–130.2) | 78.1 (42.6–104.8) | 41.7 (14.1–64.1) | 63.4 (41.7–108.0) |
| GMT | 83.9 | 73.7 | 35.9 | 65.6 |