Table 1.
MICs of selected antibioticsa for isolate 2688 (Acinetobacter pitti), E. coli Top10 plus pBSCK, and E. coli Top10 plus pBSCK-OXA-72
| Strain | MIC (μg/ml)f |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IPM | MEM | DORb | FEP | CAZ | CTX | CRO | ATMc | TZP | CSLd | AMK | TGCe | PMB | CIP | |
| A. pittii 2688 | 32 (R) | >64 (R) | >64 (R) | 4 (S) | 4 (S) | 16 (I) | 16 (I) | 32 (R) | 128/4 (R) | ≤8/4 (S) | ≤8 (S) | ≤0.12 (S) | 1 (S) | ≤0.5 (S) |
| E. coli Top10 plus pBSCKh | 0.125g | 0.012g | 0.012g | 0.032g | ≤1 | ≤1 | ≤1 | ≤2 | ≤8/4 | ≤8/4 | ≤8 | ≤0.5 | ≤0.5 | ≤0.5 |
| E. coli Top10 plus pBSCK-OXA-72h | 0.75g | 0.032g | 0.047g | 0.094g | ≤1 | ≤1 | ≤1 | ≤2 | ≤8/4 | ≤8/4 | ≤8 | ≤0.5 | ≤0.5 | ≤0.5 |
IPM, imipenem; MEM, meropenem; DOR, doripenem; FEP, cefepime; CAZ, ceftazidime; CTX, cefotaxime; CRO, ceftriaxone; ATM, aztreonam; TZP, piperacillin-tazobactam; CSL, cefoperazone-sulbactam; AMK, amikacin; TGC, tigecycline; PMB, polymyxin B; CIP, ciprofloxacin.
MICs according to EUCAST breakpoints (7).
MICs according to CLSI guidelines for Pseudomonas aeruginosa (5).
MICs according to Jones et al. (10).
MICs according to BSAC criteria (3).
Letters in parentheses indicate interpretation of MICs: R, resistant; I, intermediate; S, susceptible.
MIC values determined by Etest.
Organism was susceptible to all antibiotics tested.