Table 1.

MIC and MFC results for aminoglycosides and tigecycline against 24 Pythium insidiosum isolates^a

Antibiotic and parameter	No. of isolates (%) with the following MIC or MFC (mg/liter):										MIC or MFC range (mg/liter)	GM (mg/liter)
	0.25	0.5	1	2	4	8	16	32	64	128
Paromomycin
MIC	0	0	0	0	0	0	0	9 (7.5)	15 (62.5)	0	32–64	49.3
MFC	0	0	0	0	0	0	0	2 (8.3)	15 (62.5)	7 (29.2)	32–128	73.9
Gentamicin
MIC	0	0	0	0	0	0	0	5 (20.8)	19 (79.2)	0	32–64	55.3
MFC	0	0	0	0	0	0	0	2 (8.3)	17 (70.8)	4 (16.7)	32–128	69.7
Neomycin
MIC	0	0	0	0	0	0	0	5 (20.8)	19 (79.2)	0	32–64	55.3
MFC	0	0	0	0	0	0	0	2 (8.3)	15 (62.5)	7 (29.2)	32–128	73.9
Streptomycin
MIC	0	0	0	0	0	0	0	8 (33.3)	16 (66.7)	0	32–64	50.7
MFC	0	0	0	0	0	0	0	3 (12.5)	17 (70.8)	3 (12.5)	32–128	62.1
Tigecycline
MIC	2 (8.3)	2 (8.3)	17 (70.8)	3 (12.5)	0	0	0	0	0	0	0.25–2	0.9
MFC	0	0	10 (41.7)	2 (8.3)	7 (29.2)	5 (20.8)	0	0	0	0	1–8	2.4

^aMFC, minimum fungicidal concentration; GM, geometric mean.