Table 2.

M. tuberculosis strains used in this study

Strain	sSNP clustera	RFLPb	Resistancec	Spoligotype octal coded	PGGe	Source
H37Rv	VII	H37Rv	None	777777477760771	3	Laboratory strain, PHRIf TB Center
10536	II	KY	R, I	000000000000771	1	Clinical isolate, PHRI TB Center
10775	II	W4	None	000000000003771	1	Clinical isolate, PHRI TB Center
18996	IV	H	I, R, E, PZA	777776777760601	2	Clinical isolate, PHRI TB Center
13571	IV	H	None	777776777760601	2	Clinical isolate, PHRI TB Center
16644	V	AH	I, R, E, PZA, S	777776777760771	2	Clinical isolate, PHRI TB Center
12850	V	AH	None	777776777760771	2	Clinical isolate, PHRI TB Center

^asSNP, synonymous single nucleotide polymorphism. Isolates have been grouped based on closely related genotypes (1).

^bRFLP (restriction fragment length polymorphism) genotype method based on IS6110 (1).

^cAbbreviations: E, ethambutol; I, isoniazid; PZA, pyrazinamide; R, rifampin; S, streptomycin.

^dSpoligotyping is a PCR-based genotyping method focused on directly repeated nucleotide sequences (5).

^ePGG, principal genetic group (23, 57).

^fPHRI, Public Health Research Institute.