Fig 4.

Reversibility of CMV infection and HFF cell growth after treatment with AS, 838, and GCV. (A) Compounds were present in CMV-infected cells at the indicated intervals. Virus DNA in supernatants was quantified by real-time PCR at 6 days postinfection. VND, virus with no drug. (B) HFF cells were treated with AS, 838, and GCV for 3 days, and then 2,500 treated or untreated cells were seeded on 96-well plates and cultured in DMEM with 10% FBS. Cell viability was measured by CellTiter-Glo at 1 to 7 days after seeding. Data represent mean values (±SD) of triplicate determinations from more than three independent experiments.