Fig 3.

Transport of hydroxy, keto, and acid analogs of amino acids by CitP. Citrate consumption by resting cells of L. lactis IL1403(pFL3) is shown in the absence (△) and presence of a 2 mM concentration of the OH (○), O (●), and H (▼) analogs of glycine, i.e., glycolate (○), glyoxylate (●), and acetate (▼) (A); alanine, i.e., l-lactate (○), pyruvate (●), and propionate (▼) (B); valine, i.e., α-hydroxyisovalerate (○), α-ketoisovalerate (●), and isovalerate (▼) (C); leucine, i.e., α-hydroxyisocaproate (○), α-ketoisocaproate (●), and isocaproate (▼) (D); methionine, i.e., 2-hydroxy-4-methylthiobutyrate (○), 2-keto-4-methylthiobutyrate (●), and 4-methylthiobutyrate (▼) (E); phenylglycine, i.e., phenylglycolate (○), phenylglyoxylate (●), and phenylacetate (▼) (F); phenylalanine, i.e., phenyllactate (○), phenylpyruvate (●), and phenylpropionate (▼) (G); and tryptophan, i.e., indole-3-lactate (○), indole-3-pyruvate (●), and indole-3-propionate (▼) (H) (see Table S1 in the supplemental material).