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Replication activity of Pol II-D547N(exo−). (A) Cartoon depiction of the assay. (B) The ability of Pol II+ or Pol II-D547N(exo−) together with β+ or βR (as noted) to catalyze replication in vitro was measured as described in Materials and Methods. The results shown are averages of at least 4 independent determinations. Error bars represent standard deviations.
