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IL-10 production by cellular subsets. (A) CD4+ T cells, CD8+ T cells, CD25+ FoxP3+ Tregs, CD14+ monocytes, CD19+ B cells, CD11c+ mDCs, and CD123+ pDCs from chronically HIV-1-infected, untreated subjects were analyzed for spontneous production of IL-10 by ICS. (B) Analysis of IL-10 secretion in unstimulated PBMC subsets in 15 untreated, chronically HIV-1-infected individuals. *, P < 0.05; **, P < 0.01; ***, P < 0.001.
