Fig 3.

A functional MRN complex and ATM regulate irradiation-induced antiviral responses in primary macrophages. Nbs hypomorphic (A, B, H, and I), ATM-deficient (C to E and G), and H2AX-deficient (F) primary macrophages or macrophages derived from wt littermates were treated as described for Fig. 1 and 2, and the indicated mRNA transcripts (A to H) or proteins (I) were measured as described in Fig. 2. In panels A to H, the data were pooled from three independent experiments (two replicates per experiment) and are presented as means with the SEM. In panel I, the data are representative of two independent experiments.