Fig 2.

Detection of IE, E, and L viral protein markers in gliomas. Immunoblots show the presence of viral proteins in patient specimens. The first row in the table lists the sample identification, and the second row indicates the disease stage. GBM, glioblastoma multiforme; OD, oligodendroma; AS, astrocytoma; PA, pilocytic astrocytoma. HEL, human embryonic lung fibroblasts; I-HEL, infected HEL cells (IC, infected cells). The entries shaded in gray are patient specimens that were tested for viral copy numbers in Fig. 1B. (A) Nine of twelve (75%) patient specimens were found to exhibit IE (IE1) and E (pp65) protein expression. (B) E/L (gB55) protein expression was found in the subset of tumors expressing IE and E proteins.