Table 1. Overview of differences between existing ART programs and TasP.

Difference	Explanation
Program components	To achieve widespread and frequent HIV testing and high uptake of ART immediately following an HIV diagnosis, TasP strategies will likely require interventions that are not present in current ART programs.
Disease experiences and treatment outcomes	Disease experiences and treatment-relevant behaviors: patients who initiate ART early are less likely to experience recovery from the symptoms of the later stages of HIV disease. Lack of such experience may affect behaviors that are crucial for treatment outcomes, such as ART retention and adherence.
	Quality of life: early initiation may reduce quality of life (because it increases the duration of drug side effects and transforms people into patients several years earlier than under current ART guidelines) or improve quality of life (because it decreases the severity of drug side effects and avoids the psychologically distressing situation of having to wait for one's health status to deteriorate before being allowed to start ART).
	Economic productivity: early initiation may reduce the lifetime economic productivity of HIV-infected individuals (because it increases the total portion of lifetime spent utilizing ART) or improve productivity (because it avoids the negative economic consequences of deteriorating health preceding late ART initiation).
Patient population	In the long run, successful TasP could lead to changes in the composition of the people requiring ART, because the preventive effects of TasP may benefit some population subgroups at risk of HIV acquisition, but not others.