Table 2. Genes whose differential transcription for gestational age was replicated across the qPCR groups, also containing CpGs whose methylation levels correlated with gestational age.
Gene Name | CpG ID | CpG location | UCSC_RefGene_Group | Correlation PValue | min β-value | max β-value | Min-max range | Average β for lowest GA samples | Average β for highest GA samples | Range between highest and lowest GA |
CHRDL2 | cg13616912 | Island | TSS1500 | 0.0184 | 4% | 9% | 6% | 8% | 5% | 3% |
COL1A2 | cg18511007 | TSS200 | 0.0123 | 3% | 13% | 10% | 8% | 5% | 3% | |
CXCL14 | cg23510026 | S_Shore | TSS1500 | 0.0163 | 86% | 95% | 8% | 90% | 93% | 3% |
GLI2 | cg18835090 | Body | 0.0039 | 80% | 88% | 8% | 80% | 85% | 5% | |
GLI2 | cg23854087 | Body | 0.0292 | 78% | 87% | 8% | 80% | 83% | 3% | |
GLI2 | cg13713922 | S_Shore | Body | 0.0367 | 7% | 16% | 9% | 14% | 9% | 4% |
GLI2 | cg07855121 | Body | 0.0203 | 92% | 97% | 5% | 93% | 96% | 3% | |
GLI2 | cg15471519 | Body | 0.0476 | 73% | 80% | 7% | 75% | 76% | 1% | |
GLI3 | cg00842259 | N_Shore | Body | 0.0494 | 78% | 87% | 9% | 83% | 87% | 4% |
GLI3 | cg21536074 | Body | 0.0101 | 81% | 90% | 9% | 89% | 82% | 7% | |
GLI3 | cg01013023 | Body | 0.0268 | 84% | 96% | 12% | 87% | 90% | 3% | |
GLI3 | cg07104748 | Island | TSS1500 | 0.0463 | 0% | 2% | 2% | 0% | 1% | 1% |
GLI3 | cg12853563 | Island | TSS1500 | 0.0256 | 5% | 9% | 4% | 8% | 6% | 2% |
HSD11B1 | cg06828613 | 5′UTR | 0.0283 | 45% | 62% | 17% | 55% | 48% | 7% | |
MATN3 | cg10334703 | S_Shore | TSS1500 | 0.037 | 15% | 37% | 23% | 30% | 20% | 10% |
SMO | cg10586510 | Island | Body | 0.0423 | 9% | 14% | 5% | 13% | 10% | 3% |
SMO | cg06217803 | S_Shore | Body | 0.0111 | 74% | 84% | 10% | 76% | 79% | 3% |