Effects of bilateral MFB 6-OHDA and subsequent chronic L-DOPA (12 mg/kg, + benserazide, 15 mg/kg, sc; LD) on anxiety-like behaviors in the elevated plus maze. (A) Time spent in the open versus closed arms are denoted by black and white bars, respectively. Bars denote the effect of group on frequency of (B) head dips, (C) stretched-attend postures, and (D) rearing within the maze. Group effects were determined by one-way ANOVAs and Fisher LSD post-hocs were used to analyze specific group differences (*p<0.05 vs. Sham-VEH).