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Effects of bilateral MFB 6-OHDA and subsequent chronic L-DOPA (12 mg/kg, + benserazide, 15 mg/kg, sc; LD) on depressive-like behaviors in the forced swim test. Frequency of (A) climbing, (B) mild swimming, and (C) immobility were determined during the first 5 min of exposure and the 5 min of testing 24 h later as shown by the black and white bars, respectively. Group effects were determined by two-way repeated measures ANOVAs.
