Table 2.
Identified and Confirmed Nonmelanoma Skin Cancer Cases with Sensitivity, Specificity, Negative (NPV) and Positive Predictive Values (PPV) by Algorithm, 2007-2008. HMO-Enrollee Claims Data.
| Identification Algorithm |
True Positive Cases |
Identified Cases by Algorithm |
Confirmed True Cases Identified by Algorithm |
Sensitivity (95% CI) |
Specificity (95% CI) |
NPV (95% CI) |
PPV (95% CI) |
|---|---|---|---|---|---|---|---|
| ICD-9-CM code alone |
2506 | 2209 | 1639 | 65.4 (63.5-67.3) |
95.5 (95.2-95.9) |
93.4 (93.0-93.8) |
74.2 (72.4-76.0) |
| CPT code alone |
2506 | 2059 | 1610 | 64.2 (62.4-66.1) |
96.5 (96.2-96.8) |
93.2 (92.8-93.7) |
78.2 76.4-80.0) |
| Both ICD-9- CM and CPT codes |
2506 | 1534 | 1230 | 49.1 (47.1-51.0) |
97.6 (97.4-97.9) |
90.7 (90.2-91.2) |
80.2 (78.2-82.2) |
HMO, Health Maintenance Organization; PPV, Positive Predictive Value; CI, Confidence Interval; ICD- 9-CM, International Classification of Diseases, 9th Revision, Clinical Modification; CPT, Current Procedural Terminology.
Study Population: large integrated health system, HMO Health Plan Enrollees, southeastern MI USA.
Standard: Co-Path3 electronic histopathology data.
Total Skin Pathology Cases: 15,297